James J. De Yoreo

Affiliate Professor of Chemistry and Materials Science & Engineering
Portrait of Jim De Yoreo wearing a suit and tie

Contact Information

Pacific Northwest National Laboratory
Accepting new graduate students


Ph.D. Cornell University, 1985

The research interests of the De Yoreo group can be broadly categorized as understanding and manipulating the physics of interactions and assembly at solid-liquid interfaces in nanoscale, biological, biomimetic, and environmental systems. The primary techniques used in support of this work are in situ scanned probe microscopy and in situ transmission electron microscopy (TEM), in combination with theoretical analysis.

Specific research topics include the following:

  • Assembly and aggregation in biological and biomimetic systems: biomineralization; protein aggregation and self-assembly; virus and protein organization at nanoscale chemical templates.
  • Environmental and technological crystallization: Molecular-scale controls on mineral formation and crystal growth: Calcium carbonate, oxalate and phosphate minerals; protein crystal growth.
  • In situ scanned probe microscopy: molecular imaging; force spectroscopy; chemical nano-lithography; material transport at tip-surface contacts.
  • In situ transmission electron microscopy: development of fluid cell imaging; dynamics of nucleation, protein matrix-directed mineralization, oriented attachment, mesocrystal formation.