Fields of Interest
Biography
Matt Bush pursued his Ph.D. with Evan Williams and Richard Saykally at the University of California, Berkeley. During that time, he used laser spectroscopy and Fourier-transform mass spectrometry to investigate zwitterion formation and the effects of hydration on the structures of ions. He then joined the laboratory of Carol Robinson FRS DBE at the University of Cambridge and the University of Oxford. During that time, he was a Waters Research Fellow, a Junior Research Fellow of Jesus College, University of Oxford, and developed experimental and analytical frameworks for using ion mobility mass spectrometry to characterize the structures of biological molecules and their complexes. He joined the chemistry faculty at the University of Washington in 2011, where he is also a member of the Department of Biochemistry, the Biological Physics, Structure and Design Program, and the Molecular Engineering & Sciences Institute.
Research in the Bush lab focuses on developing new mass spectrometry based approaches for elucidating the structures, assembly, and dynamics of biological molecules. His group applies these approaches to a wide range of biological systems, with a focus on those involved in protein homeostasis.